Jonathan McConathy Selected Research

Propionates

1/2018	Amino Acid Uptake Measured by [18F]AFETP Increases in Response to Arginine Starvation in ASS1-Deficient Sarcomas.
1/2015	System a amino acid transport-targeted brain and systemic tumor PET imaging agents 2-amino-3-[(18)F]fluoro-2-methylpropanoic acid and 3-[(18)F]fluoro-2-methyl-2-(methylamino)propanoic acid.
7/2013	18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas.
12/2010	Click synthesis and biologic evaluation of (R)- and (S)-2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid for brain tumor imaging with positron emission tomography.
1/2010	Synthesis, radiolabeling, and biological evaluation of (R)- and (S)-2-amino-3-[(18)F]fluoro-2-methylpropanoic acid (FAMP) and (R)- and (S)-3-[(18)F]fluoro-2-methyl-2-N-(methylamino)propanoic acid (NMeFAMP) as potential PET radioligands for imaging brain tumors.
5/2002	Radiolabeled amino acids for tumor imaging with PET: radiosynthesis and biological evaluation of 2-amino-3-[18F]fluoro-2-methylpropanoic acid and 3-[18F]fluoro-2-methyl-2-(methylamino)propanoic acid.

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Jonathan McConathy Research Topics

Disease

19	Neoplasms (Cancer) 10/2018 - 05/2002
14	Brain Neoplasms (Brain Tumor) 03/2018 - 05/2002
7	Glioma (Gliomas) 01/2019 - 12/2008
6	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 07/2012
5	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 04/2015
5	Gliosarcoma 12/2010 - 05/2002
2	Tauopathies 01/2022 - 01/2016
2	Dementia (Dementias) 07/2016 - 04/2015
2	Cognitive Dysfunction 01/2016 - 04/2015
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2013 - 07/2012
1	Heart Failure 01/2020
1	Multiple Myeloma 10/2018
1	Sarcoma (Soft Tissue Sarcoma) 01/2018
1	Starvation 01/2018
1	Osteosarcoma (Osteogenic Sarcoma) 01/2018
1	Glut1 Deficiency Syndrome 01/2017
1	Neurodevelopmental Disorders 01/2017
1	Inflammation (Inflammations) 07/2016
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 07/2016
1	Nervous System Diseases (Neurological Disorders) 07/2016
1	Neurologic Manifestations (Neurological Manifestations) 07/2016
1	Vasculitis (Vasculitides) 07/2016
1	Glioblastoma (Glioblastoma Multiforme) 07/2013
1	Colorectal Neoplasms (Colorectal Cancer) 01/2013

Drug/Important Bio-Agent (IBA)

19	Amino Acids FDA Link 01/2019 - 05/2002
9	Biological ProductsIBA 11/2015 - 05/2002
8	AcidsIBA 04/2016 - 05/2002
6	PropionatesIBA 01/2018 - 05/2002
4	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2016
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 10/2018 - 07/2013
3	Amino Acid Transport Systems (Amino Acid Transporter)IBA 10/2018 - 01/2013
3	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 01/2015
3	(18F)fluoroethyltyrosineIBA 04/2016 - 01/2013
2	AndrogensIBA 01/2021 - 09/2018
2	fluorodopa F 18IBA 10/2018 - 03/2018
2	Tyrosine (L-Tyrosine)FDA Link 04/2016 - 01/2013
2	LigandsIBA 01/2016 - 05/2002
2	Fluorine-18IBA 12/2008 - 05/2002
2	Carboxylic AcidsIBA 06/2003 - 05/2002
1	Mineralocorticoid Receptor AntagonistsIBA 01/2020
1	acifluorfen (Blazer)IBA 01/2019
1	Melphalan (Alkeran)FDA LinkGeneric 10/2018
1	Green Fluorescent ProteinsIBA 10/2018
1	Dihydrotachysterol (AT 10)IBA 03/2018
1	Bevacizumab (Avastin)FDA Link 03/2018
1	Arginine (L-Arginine)FDA Link 01/2018
1	Basic Amino Acid Transport SystemsIBA 01/2018
1	Histidine (L-Histidine)FDA Link 01/2018
1	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 01/2018
1	ADI PEG20IBA 01/2018
1	Contrast MediaIBA 10/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Glucose Transporter Type 1IBA 01/2017
1	tau Proteins (tau Protein)IBA 07/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2016
1	CarbonIBA 04/2016
1	HydrogenIBA 04/2016
1	SodiumIBA 05/2015
1	Glutamine (L-Glutamine)FDA Link 05/2015
1	Biomarkers (Surrogate Marker)IBA 04/2015
1	Oxygen (Dioxygen)IBA 01/2015
1	Phenylalanine (L-Phenylalanine)FDA Link 05/2013
1	Complement System Proteins (Complement)IBA 04/2013
1	Large Neutral Amino Acid-Transporter 1IBA 01/2013
1	Zirconium-89IBA 01/2013
1	TriazolesIBA 12/2010
1	Iodine-123IBA 12/2008
1	Radioisotopes (Radionuclides)IBA 12/2008
1	Deoxyglucose (2 Deoxy D glucose)IBA 12/2008
1	3- fluoro- 2- methyl- 2- (methylaminio)propanoic acidIBA 05/2002
1	1- amino- 3- fluoromethylcyclobutane- 1- carboxylic acidIBA 05/2002
1	2-amino-3-fluoro-2-methylpropanoic acidIBA 05/2002
1	2-aminoisobutyric acidIBA 05/2002
1	3- fluoro- 2- methyl- 2- (methylamino)propanoic acidIBA 05/2002
1	RadiopharmaceuticalsIBA 05/2002

Therapy/Procedure

5	Therapeutics 01/2021 - 01/2013
2	Intravenous Injections 07/2013 - 05/2002
1	Radiotherapy 01/2021